Nanomedicine
THE TOPICS COVERED IN THE EDITED BOOK WILL INCLUDE, BUT ARE NOT LIMITED TO:
Nanotechnology in:
– Tissue Engineering & Biomaterial Science
– Nanoscale tissue scaffolds
– Nanoscale biomaterial surface modification
– Enzyme responsive tissue scaffolds
– Guiding stem cell differentiation
Diagnosis and Imaging:
– Biosensors
– Quantum Dot Imaging
– Image enhancing particles
Drug Delivery (Nano-Pharmacology):
– Targeted drug delivery
– Nano-vehicle delivery systems
– Photo-dynamic therapy
– Thermo-diagnostics
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Preface
Author(s): Professor Alexander Marcus Seifalian, Dr Achala de Mel, Dr Deepak Kalaskar
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Chapter 1
Long Circulating Nanoparticles for Tolerogenesis
Author(s): Amy Tekrony, Vincent Wright, Anne Slaney, Usama Al-Atar, Amy Frederick, Teresa Rodriguez, Jillian Buriak, David Cramb, Lori West
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Chapter 2
In Vivo Applications of Quantum Dot Nanoparticles for Optical Diagnostics and Therapy
Author(s): Elnaz Yaghini, Alexander M. Seifalian, Alexander J. MacRobert
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Chapter 3
Conjugation of Gold nanoparticles and liposomes for combined vehicles of drug delivery in cancer
Author(s): Sara Figueiredo1, Rita Cabral, Daniel Luís, Alexandra R. Fernandes and Pedro V. Baptista
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Chapter 4
Multifunctional Core-Shell Nanostructures
Author(s): M. Clara Gonçalves , M. Barbara Martins
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Chapter 5
Biomaterial surface modification of titanium and titanium alloys for medical applications
Author(s): Mukta Kulkarni, Anca Mazare, Patrik Schmuki, Aleš Iglič
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Chapter 6
Author(s): Masayuki Ishihara, Makoto Takikawa, Hidemi Hattori, Masanori Fujita, Miya Ishihara and Shingo Nakamura
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Chapter 7
Nanophysical approach to diagnosis of epithelial tissues using Opto-magnetic imaging spectroscopy
Author(s): Lidija Matija, Branislava Jeftić, Gorana Nikolić, Aleksandra Dragičević, Ivana Mileusnić, Jelena Munćan, Djuro Koruga
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Chapter 8
Solid lipid nanoparticles – a promising drug delivery system
Author(s): Hristo Svilenov, Christo Tzachev
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Chapter 9
Author(s): Francisco Bulnes, F H. Bulnes-Gonzalez
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Chapter 10
Optimization of perfluorocarbon nanoemulsions for molecular imaging by 19F MRI
Author(s): Christoph Grapentin, Friederike Mayenfels, Sabine Barnert, Regine Süss, Rolf Schubert
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Chapter 11
Designing polymeric nanoparticles for targeted drug delivery system
Author(s): Ida Idayu Muhamad, Suguna Selvakumaran, Nurul Asmak Md Lazim
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Chapter 12
Author(s): Lu-Ning Wang, Ming Jin
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Chapter 13
Unsupervised medical image segmentation using stochastic optimization methods
Author(s): Ivan Cruz-Aceves, Juan Gabriel Avina-Cervantes, Juan Manuel Lopez-Hernandez, Ma. de Guadalupe Garcia-Hernandez, Miguel Torres-Cisneros, Manuel Ornelas-Rodriguez
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Chapter 14
Biological applications of Semiconductor Nanoparticles
Author(s): Salam Massadeh, Manal Alaamery
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Chapter 15
Biosensors and nanobiosensors: design and applications
Author(s): Ahmed Touhami
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Chapter 16
Titanate Nanotubes as a Versatile Platform for Nanomedicine
Author(s): Julien Boudon, Anne-Laure Papa, Jérémy Paris and Nadine Millot
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Chapter 17
Bismuth nanoparticles: antimicrobials of broad-spectrum, low cost and safety
Author(s): Cabral-Romero Claudio, Shankararaman Chellam
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Chapter 18
Surface Modification of Porous Anodic Alumina for Medical and Biological Applications
Author(s): Morteza Aramesh and Jiri Cervenka
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Chapter 19
Author(s): Lenka Kolářová, Petr Vaňhara, Eladia María Peña-Méndez, Aleš Hampl, and Josef Havel
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Chapter 20
Recent trends in tissue engineering applications of atom transfer radical polymerization
Author(s): Masoud Mozafari, Vahid Shabafrooz, Mostafa Yazdimamaghani, Daryoosh Vashaee b, Lobat Tayebi
Professor Alexander Seifalian
University College London (UK)
Alexander Seifalian is Professor of Nanotechnology and Regenerative Medicine and is director of Centre for Nanotechnology, Biomaterial and Tissue Engineering. He has been the driving force behind the Centre’s development of bypass grafts, stents, heart valve, nerve regeneration, cartilage drug delivery and patent filing and commercialisation. He has received grant support of over £3.8 million from research councils and industry over the past 4 years. Professor Seifalian has been extensively involved in commercialisation of medical devices, including: i) the development of a vascular by-pass graft funded by MedLink Projects, this being based on poly(carbonateurea) urethane (PCU) with a commercialised version used in renal dialysis; ii) the development of a miniature implantable portal blood pump (EEC Funded) currently under clinical trial; iii) the development of a laser light activated vascular sealant, which has now been commercialised; and iv) synthesis of polymeric scaffolds for academic and commercial use. His research team has been awarded the top prize by Medical Future 2007 for development of cardiovascular devices including bypass grafts using the family of new innovative materials. He has over 266 peer review publications and 21 book chapters. He is a Fellow of Institute of Nanotechnology.
Achala de Mel
University College London (UK)
Achala de Mel is a lecturer in Regenerative Medicine at UCLs Division of Surgery and Interventional Sciences, and a member of the UCL’s centre for Nanotechnology and Regenerative Medicine. Her primary interests are in optimising cell-material interactions for Regenerative Medicine applications. Together with Prof Alexander Seifalian she is currently leading a research team funded by the EPSRC on 3D printing of thermoplastic nanocomposites for surgical implants.
Deepak M. Kalaskar
University College London (UK)
Dr Deepak Kalaskar is Team Leader in development of artificial organs at University College London (UCL). He is actively involved in research on nanotechnology and tissue engineering solutions for artificial organs in Prof Seifalian’s team. He had worked previously, at various universities in UK and Belgium on number of developmental and applied research projects which include high throughput culture for embryonic stem cells, Nanomaterials coatings for orthopaedic implants, protein based nanoparticles for drug delivery applications, on demand printing of cells using inkjet printer. His primary interest includes development of smart materials for nanomedicine, modification of biomaterial interfaces using Plasma polymerisation and 3D printing of various artificial organs and their surface modification.
He also heads MSc course in Burns, Plastic and Reconstructive Surgery at Royal Free Hospital campus of UCL, which is directed towards training scientists and clinicians in field of Regenerative Medicine and Nanotechnology. He works as a consultant for UCL with various healthcare industries in UK and Europe.